The Santa Fe Animal Shelter of New Mexico said Meow, who weighed 40 pounds, died of pulmonary failure.
The two-year-old cat had been surrendered to the shelter as his 87-year-old owners could no longer take care of him.
Employees at the shelter had been working to put Meow, who weighed the equivalent of a 700 pound, on a diet so he could shed weight and be adopted.
Four different veterinarians fought to save the cat’s life to no avail, the shelter’s Mary Martin said on Facebook.
‘The shelter staff – along with all those who met Meow during his short time with us – mourn his passing,’ she said in a statement.
‘Meow had been doing so well in his foster home; walking up stairs and seeking affection – that it is so very hard to believe he is gone.’
She added: ‘We will forever be grateful for the attention Meow’s size brought to pet obesity and to animal shelters across the country. We are especially grateful to all of you who fell in love with this charming cat – as we did – and were so very interested in his progress and success.’
The shelter had previously described Meow as ‘very sweet’ but warned he faced similar health risks to those experienced by a ‘morbidly obese person’.
‘We got him a scratching post with a carpeted ring attached but he couldn’t even get his head through,’ spokesman Ben Swan said.
‘He had no interest in the super-sized toy mouse we gave him either.’
The fattest cat in history recorded by Guinness World Records is Himmy from Australia, who weighed 35 pounds.
But the category was later scrapped amid concerns it would encourage over-feeding of pets.
This is asham that he was aloud to get so fat,he was a lovely color he could have live longer
so sad .. unfortunately owners equate food with love (for both pets and children) .. please keep your pets healthy
I would like to thank you for the efforts you've put in writing this blog.I'm hoping the same high-grade site post from you in the future as well.In fact your creative writing.
[...] fattest cat dies. Makes [...]
[...] Raise the world’s new fattest house cat. Marvel at the fact that no matter how fat the cat gets, it’s face stays the exact same [...]
Awww…so sad
but at least he knew what it was to be loved…so many pets live years without getting the attention and love that Meaw got 
RIP Meow!!! He obviously will be missed and never forgotten 
[...] post is in response to the world’s fattest cat recently dying – see the Weekly World News Article here. Awful as this was to see a moggy mistreated – yes over feeding your cat is not good [...]
what the heck do they mean by " who weighed the equivalent of a 700 pound" equivalent to what? it makes no sense.
this cat is really fat
i never asw him untell now [R.I.P. you are still a good cat]
good cat
relly good cat
im really cyeing
There is a tater cat than meow search google for fat cats then click on images there is a fatter cat on there