INBREEDING TURNS APPALACHIANS BLUE

Inbreeding in eastern Kentucky has been turning offspring blue since the early 1880s.
Dating back to the early 1800s, an isolated family in eastern Kentucky – who can trace their roots back to a French orphan – started producing children who were blue.
As a result of a coincidental meeting of recessive genes, intermarriage and inbreeding, members of the Fugate family were born with a rare condition that made them visibly discoloured.
The mystery behind the astonishing picture of the Fugates, which has been baffling people for years, appears to have finally been solved.
It began when Martin Fugate, a French orphan, settled on the banks of eastern Kentucky’s Troublesome Creek to claim a land grant in the early 19th century.

 He married a red-haired American named Elizabeth Smith – who had a very pale complexion – and their union formed a genetic mutation that resulted in their descendants being born with blue skin.
Called methaemoglobinaemia (commonly known as met-H), the condition reduces the individual’s ability to carry oxygen in their blood. As a result, their blood is darker than the color typically found running through people’s veins.

The Fugate family intermarried with a neighbouring family for generations, which led to a relatively ‘pure’ gene pool, often including the met-H gene.
But as Kentucky became more populated and more genes came into the Fugate family tree, there were far fewer children born blue.
The gene is still around today but has now become statistically insignificant and there are no serious medical problems associated with it.

Because the Fugate family lived in such an isolated part of the Kentucky, they intermarried with a neighboring family for generations which led to a relatively ‘pure’ gene pool where the met-H gene appeared much more frequently.
The family was first discovered in 1958 when one of the blue men, Luke Combs, who was a descendant of another branch of the Fugate family, took his white wife to the University of Kentucky Hospital and doctors paid more attention to him than his wife.
‘Luke was just as blue as Lake Louise on a cool summer day,’ doctor Charles H. Behlen II told the Tri-City Herald in 1974.
Aside from the stark discoloration of the carrier’s skin, there are no serious problems associated with the disease.
In 1980, a counter-intuitive solution was discovered where the blue person drinks a chemical-filled solution that is itself blue. This then turns the carrier’s blood into a ‘normal’ red hue which is then reflected in a change in skin tone.
The methaemoglobinaemia condition, or ‘met-H’, reduces someone’s ability to carry oxygen in the blood, leaving it darker than the colour typically found in veins.

The Fugate family intermarried with a neighbouring family for generations, which led to a relatively ‘pure’ gene pool, often including the met-H gene.
But as Kentucky became more populated and more genes came into the Fugate family tree, there were far fewer children born blue.

The gene is still around today but has now become statistically insignificant and there are no serious medical problems associated with it.
Because of the dispersion of fluids, the solution only lasts for about a day so the carrier would have to drink a serving every day.

‘They weren’t sick; it was just the way they look. They’re normal people – they’re good people’
DailyMail

These people aren’t related to the Fugates:

15 thoughts on “INBREEDING TURNS APPALACHIANS BLUE”

  1. I was actually born with my twin sisters fetus inside me. 5 years ago when I was on a swingerparty she got pregnant with me. Today I have a healthy son/nephew who is slightly green in skincolor. He came from where the sun don't shine. It was painful.

  2. martin fugate was blue from birth, which has nothing to do with inbreeding. he passed the gene on to his children. his wife happened to be a carrier for the gene, so in turn about half of their children were blue. there is no "blue-soloution" that turns them back to a "normal" color. it is a blood disorder in which their blood does not oxygenate correctly. the mans picture at the bottom got his unusual color from taking silver nitrate which will turn anyone blue if it is taken over a long period of time.
    get your facts straight for petes sake.

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